Saturday, December 28, 2019

Dreadful Freedom- an Essay Depicting Andy Dufresne as an...

To be a true existential hero means many things. The majority of a persons actions must be in accordance with the strictly defined beliefs of an existentialist. An existential hero is very conscious of the worth and impact of his choices. He is responsible, lonely, independent, self-reliant and free. Andy Dufresne the protagonist in The Shawshank Redemption written by Stephen King and directed by Frank Darabont exhibits these essential existential qualities. The movie has several existential themes within it, made apparent by Andy’s words and actions. For this reason, it is evident that Andy Dufresne is an existential hero. In existential philosophy, a great deal of importance is placed on the concept of choice. An existential hero†¦show more content†¦Meaning does not come from external events, forces, or material items. I could be argued that Andy Dufresne does not meet this qualification. Andy is not contented with the poor supply of books in the prison library, but rather sends hundreds of letters requesting money for more books. This behavior suggests that Andy places value on â€Å"thing-ness† a very non-existential trait. However, Andy uses the books to build for himself and his fellow inmates a great library where he teaches and helps many to get their high school diplomas. It can be concluded therefore, that Andy was not placing value in the thing-ness of books, but rather the self-improvement that comes from educating oneself. When Andy was sent to the hole for weeks, without the any of the external extremities that most rely on, the unnaturally long sentence should have been e nough to drive a person to near-madness. However, the solitude had little effect on Andy. The music inside of him was enough o keep up his moral. This is because, for Andy, his meaning is found within himself, an attribute absolutely necessary for an existential hero. Andy Dufresne is well aware of the control he has over his own life. His actions are not reflective of societies rules or conventions and he is conscious of the scope of his influence. Much of his life he has been lonely and independent. He does not value material things, and his meaning is found within himself. In

Friday, December 20, 2019

Themes Of Walter In A Raisin In The Sun - 891 Words

â€Å"If you want to live a happy life, tie it to a goal, not to people or things,† (Albert Einstein). Lorraine Hansberry, A Raisin in the Sun, March 11, 1959. In A Raisin in the Sun, the Younger family are African-American in a time where there was racial discrimination. They have aspirations of doing great things, but struggle with maintaining relationships with those around them. In the play, a conflict emerges that can change the familys lives forever. Lorraine Hansberry reveals one of her themes through the character of Walter. In the beginning of the play, Walter seems to be a childish and self-obsessed person, but he has ambitions of pursuing his dreams. In the play, Walter says, â€Å"I’m thirty five years old; I been married eleven years†¦show more content†¦When Ruth, Beneatha, and Mama see Walter acting like this, they are shocked and are disappointed in how he is acting. Walter tries to cope with the current situation he is in, and he realizes that his family is by his side and that is what matters to him in that moment. In the end, Walter comes to a realization when Travis is looking upon him that he does not want to give up his dignity, he steps up and becomes a man for his family. â€Å"And we have decided to move into our house because my father- my father- he earned it for us brick by brick.† This signifies that the money they still have would be invested into the house because they could create new memories and aspirations there. The family all had plans of doing somethi ng with the money, but in the end, they all agreed upon purchasing the house and that can represent that family can stay together during tough times and hardships. â€Å"What I mean to tell is that we come from people who had a lot of pride. I mean- We are very proud people† The Younger family know that Walter has finally become a man, and they are very proud of him. Walter will not give up on himself and his family, he will remain ambitious and face the future with his family.Show MoreRelatedExamples Of Racism In A Raisin In The Sun1672 Words   |  7 PagesAmerican history. However, not many books have been able to display the ethnic ignorance that white people have towards blacks. One of the more successful stories is A Raisin in the Sun shares a compelling story about an African-American family during the 1900s and offers many themes about social class and race. In A Raisin in the Sun, a negative legacy is left on modern drama due to the many examples of poverty and the message of money in the novel; though some people may believe that the play wasRead MoreTimeless Themes A Raisin in the Sun by Lorraine Hansberry1306 Words   |  6 PagesOne of the most notable plays on the topic of racial minorities and family issues, A Raisin in the Sun by Lorraine Hansberry, has continued to be popular since it was written in 1959. The play is about an African American family, consisting of five members, who live in Southside Chicago during the post-World-War-Two era. The Younger family is crowded in a tiny, worn, and shabby apartment and they are fairly poor. They never have much surplus money until Walter’s father, and Mama’s husband, died andRead MoreEssay on Compare Contrast a Raisin in the Sun1026 Words   |  5 PagesFrontina Taylor English Comp II Jaime Barrett Compare and Contrast A Raisin In The Sun Essay In the play, A Raisin in the Sun, by Lorraine Hansberry, and 1961 movie written by Lorraine Hansberry and presented by Columbia pictures, one of the most important themes is the American Dream. Many of the characters have hopes and dreams. They all strive towards their goals throughout. However, many of the characters have different dreams that clash with each other. Problems seem toRead MoreThe Authors Experiences of Opression in Loraine Hansberry’s â€Å"A Raisin in The Sun† and Milcha Sanchez-Scott’s â€Å"The Cuban Swimmer† 891 Words   |  4 PagesHansberry’s â€Å"A Raisin in The Sun† and Milcha Sanchez-Scott’s â€Å"The Cuban Swimmer† both capture the authors’ past experiences of oppression, and convey their struggles with identity. Both authors are from minority cultures, and both describe the same harsh pressures from the dominant culture. Both author’s share situations of being outcasts, coming fr om different racial backgrounds and trying to triumph over these obstacles. A Raisin in the Sun and The Cuban Swimmer both share common themes, themes of discriminationRead MoreLorraine Hansberry s A Raisin1120 Words   |  5 Pagesâ€Å"A raisin in the sun† was written by Lorraine Hansberry. The play was not expected to do so well because it had one white cast member, an inexperienced director, and an untried playwright. Set in the south side of Chicago in the 1950s, the play begins in the morning in the Youngers apartment. Their apartment has two bedrooms, one for mama and Beneatha, and one for Ruth and Walter, while Walter’s son Travis sleeps on the couch in the living room. Ruth gets up first and talks and Walter and TravisRead MoreAnalysis Of `` Lorraine Hansberry `` And Langston Hughes Essay1393 Words   |  6 Pagess story, Raisin in the Sun, is about a poor African-American family that try to move into a different neighborhood and break free from poverty. Also, Langston Hughes poem, Theme for English B, is about a black student who explains to his professor what is true for black or white people and that everyone is the same. Beneatha from Raisin in the Sun and the black student from Theme for English B would agree with David Wallace s ideas in his commencement speech. On the other hand, Walter from RaisinRead MoreElements used in Raisin in the Sun Essay1234 Words   |  5 Pagesï » ¿Drama 160 Term Paper: Raisin in the Sun Lorraine Hansberry’s Raisin in the Sun is a monumental play in the theatrical world. Produced in 1959, it became the first play written by an African-American woman to hit the stage and was later nominated for several Tony Awards. The play touched many controversial themes of the time including racial discrimination and poverty. The design of Raisin in the Sun, including scenic, costume, lighting, and sound elements, were crucial to developing the plotRead More Lorraine Hansberrys A Raisin In The Sun Essay575 Words   |  3 PagesConflict in A Raisin in the Sun amp;#9;In the play A Raisin in the Sun, the playwright Lorraine Hansberry depicts the life of an impoverished African American family living on the south side of Chicago. The Youngers, living in a small apartment and having dreams larger than the world in which the live, often use verbal abuse as a way to vent their problems. Many times, this verbal abuse leads to unnecessary conflict within the family. The most frequently depicted conflict is that between Walter and hisRead MoreA Raisin In The Sun American Dream Essay1669 Words   |  7 Pagesmale property owners. The rights were extended to slaves and women after the Emancipation Proclamation and 19th Amendment respectively. The American Dream became a popular theme for literature. One of the many famous literary pieces about the American Dream i0 â€Å"A Raisin in the Sun.† Written by Lorraine Hansberry, â€Å"A Raisin in the Sun† depicts the struggles of a family of African-Americans trying to achieve their America n Dream: financial stability and equality and acceptance in society. In this playRead MoreComparing Soul Food and A Raisin in the Sun Essay655 Words   |  3 PagesComparing Soul Food and A Raisin in the Sun Lorraine Hansberrys A Raisin in the Sun and George Tillmans box-office hit Soul Food explore the hardships and trials of black family life, and through the characters, setting, and theme of both the story and the film, the issue of class and the search for community is discussed. The theme indicated in these stories is the search for community. Mama Younger wanted her family to come closer. The more she tried, the farther apart they became

Wednesday, December 11, 2019

Pharmacodynamics and Potential Adverse Effects

Question: Describe about the Pharmacodynamics and Potential Adverse Effects? Answer: A: Pharmacokinetics- This concept refers to the manner a body usually reacts to various drugs. This explains largely about physiological matter which occurs once the drug enters into a body. However, the concept of pharmacokinetics includes absorption, breakdown, distribution and clearance of drugs from a human body. B: Pharmacodynamics: This concept relates to the biochemical as well as physiological processes underpinning actions of drugs, that is mechanism of actions of drugs, reflecting how drugs impact upon body. It involves physical action as well as chemical actions , also through actions of receptor/enzymes. Plasma protein binding: This concept means abilities of drugs to bind proteins along with blood plasma. Considerable level of influences of plasma protein bond upon metabolism of drugs and removal of protein included drugs refers to the increment within the drugs half-life. In addition, the extent to which drug may be added to plasma proteins impacts upon its distribution in multiple ways. Binding of Plasma protein tends to lessen the drug availability for act of diffusion or transporting to the target organ of drug since generally, only the unbound drug form can capably diffusing across membranes (YOKOMASU et al., 2008). Plasma protein binding can also lessen the transportation of drugs towards nonvascular compartments like adipose tissue. On account that a highly protein-included drug intends to stay in the systemic circulation, the drug bears a relatively less volume of distribution. Co-administration of several drugs, each being is highly bound towards plasma protein may lead to a greater than expected concentration of plasma of free form including one or more drugs. This may even occur due to the competence of co-administered drugs for similar binding place upon plasma protein. Increasing concentration of free drug may have have the potential to result in enhanced therapeutic or toxic impacts of drug. 3: A patient involved in consuming anticoagulant drug warfarin must not be recommended with salicylate drug aspirin simultaneously unless these people undergo vascular surgery. It is because both of the mentioned drugs include protein bound, also that aspirin possess much stronger affinity for proteins than that of warfarin; therefore aspirin (strong binder) dislocates warfarin (weak binder). Minute amounts of drug warfarin joins to protein places and so highly active warfarin (free drug) exists within the blood, quite like administering dos enhanced age of warfarin. It may poison the patient as well as result in heavy bleeding, and sometimes even prove more fatal, as warfarin is considered as a highly toxic drug as well as aspirin is said to intensify actions as well as effects of the drugs. Aspirin is said to offer alternatives to individuals that possessed blood clots within the deep veins. It usually never bears the prolonged utilization thinner blood. On the other side, prolonged utilization of warfarin is not appropriate at all and rather inconvenient (Yang and Rodrigues, 2010). Thus, using aspirin within the administered anticoagulant can impact upon the block of vitamin K. Block of vitamin K restricts clotting of blood which gets increased at the time of preparing fibrin. The aspirin when utilized to care for the patients, these drugs do not restrict the blood chemical from working thrombin. 4: Hepatic first pass effect means the process in which drugs pass to the bloodstream or even the lymph directly from the intestine, and from there towards the liver to get metabolised as well as largely destroyed. The importance of emphasizing upon hepatic first pass impact while administering oral drugs refers to the fact that majority of drugs are usually metabolized by liver. Here, only a small amount of any active drug moves from liver to any other circulatory systems. But, availability of the drug may be referred as considerably lessened by the first pass technique. Other means of drug administration like intravenous, sublingual, intramuscular and suppository may in fact evade such first pass effect since they allow drug absorption into systemic circulation (Wright, 2000). Main four primary systems which impact first pass effect of drugs are the enzymes of the gastrointestinal lumen, bacterial enzymes, gut wall enzymes, and hepatic enzymes. The drug absorption is specifically d etermined by the bioavailability of drugs like a drug which bears poor absorption when these are administered orally may be induced using different routes like intravenously or inhalation for example. 5: Half life: This concept refers to required time in the process of concentration of serum plasma within the human body for decreasing to half (50%); at least four or five half-lives to steady state. Prescribers often face several potential issues related to drugs administration; nevertheless quite imperative for these prescribers to accept factors which impact half life of drug like that of structure of drug, individual ability of drug metabolising, age, weight, lipophilic nature of the drug, stomach acidity (pH) and that of intestines (Bae et al., 2009). 6: The concept of Steady state concentration of drug means concentration achieved on administering drug equally to the quantity of drug removed within single dosing interval leading to a constant level of serum drug. As repeated drug doses are administered, the plasma concentration develops that reaches a level of steady state. It is when the level of drug within the plasma has developed a concentration extent which is therapeutically effective. As long as regular doses would be administered for balancing the level of drug that is cleared the drug would remain active(Banker and Clark, 2008). The normal time that is taken for reaching the steady state is around four or five times the half life of such a drug. 7: Characteristics of enzymes: In a chemical manner, normally enzymes are globular proteins (for instance, molecules of RNA and ribosome) that are basically found within nuclear cellular areas. These enzymes are basic reactants which usually break down highly complex chemical compounds. These permit occurrence of chemical reaction which has a fast property suitable for supporting life. These enzymes are not changed at the time of chemical reaction, remain available only in small amounts within cells; however, these are quite specific for their own substrate. The distinction between competitive as well as non-competitive inhibition refers to the fact that during competitive inhibition process, drug normally resembles that of an enzyme substrate or natural receptor, and so said to compete with specific natural substrate to bind into the site of binding upon the enzyme(Caldwell, 2005). For instance, specific antimicrobials like sulphonamides as well as bactrim possess same structure of para-4-aminobenzoic acid (PABA). The sulphonamides is said to compete to bind to any enzyme which prepares folic acid from PABA; so this inhibits chemical reaction. During the process of non-competitive inhibition, normally drug does not reflect natural substrate, yet binds to another alternative place upon the enzyme, and then changes the entire structure of the receptor or enzyme so that no longer it may bind with any natural substrate. For instance, heavier metals such as mercury, arsenic, carbon monoxide usually bind irreversibly with haemoglobin at place apart from oxygen. 8: Agonist usually refers to a drug that changes the physiology of any cell by means of bind with a plasma membrane or even intracellular receptors like nor-adrenaline or nor-epinephrine. Antagonist means a drug which blocks the receptor to prevent endogenous neurotransmitters from binding. Any drug which acts as an antagonist actually blocks responses initiated by agonists. Here, Atropine is said to work by binding with any acetylcholine receptors at nerve synapse, thereby allowing no messages to transmit (Chengliang, 2012). Main impacts of atropine include an increase of heart rate along with sometimes a tachycardia and inhibition of secretions (that causes a dry mouth) as well as relaxation of smooth muscle within the gut, biliary tree or urinary tract. As atropine passes the barrier of blood brain, central nervous system impacts may be experienced like during amnesia, confusion or excitation. Dilation of pupil as well as paralysis of accommodation takes place, along with an enhancement of intraocular pressure particularly within patients suffering from glaucoma (Doern, 2001). Other advantageous impacts of such atropine are its ability for decreasing gastrointestinal secretions, gastric juice, and motility specifically for patients having peptic ulcers. 9: Phenelzine as well as broad beans: both these drugs have impacts upon serotonin which is a chemical existent in brain. If these substances get combined, possibility of danger may arise that may cause severe effects with excessive accumulation of chemical serotonin within the brain. Tetracyclines as well as antacids: at some phase antacids include aluminium that may combine along with tetracycline including the amount of it absorbed within the body and this may be reduced drastically (EL-LAKKANY and NOSSEIR, 2007). Therefore, lesser effective tetracycline would be available within the body for utilizing. Therefore, it may fail to prove effective in targeting or even fighting infections. Alcohol as well as diazepam: Alcohol as well as diazepam form central nervous system depressants which mean that they may reduce activity of brain. Consequently, consumption of alcohol during ongoing treatment with this diazepam can cause serious negative reactions resulting in impaired judgment. For daily consumption of alcohol, often liver enzymes get stimulated constantly that induces tolerance towards the drug and thereby reducing the impacts(Tominaga, 2002). Part of the autonomic nervous system of Mr.FT which is affected by Malathion constitutes parasympathetic nervous system. Like all organophosphate insecticides, Malathion inhibits the acetylcholinesterase as well as alters transmission of cholinergic synaptic. Hence, when parasympathetic division gets activated, it would lead to production of some major effects such as pupil constriction, secretion from digestive glands like that of salivation, duodenal glands, gastric glands, pancreas, intestinal glands, and the liver, also vomiting as well as diarrhoea, enhanced activity of smooth muscle with gastrointestinal tract, decreased heart rate, constriction of bronchi and also negative inotropic impacts, contracting of urinary bladder during urination, and relaxation of rectum at the time of defecation (Hee Lee, 2000). Various sorts of tissue receptor which are likely to get affected are that of muscarinic (located at junction of cholinergic neuromuscular within division of parasympathetic, also some within sympathetic division) as well as nicotinic (located upon surfaces of ganglionic cells of parasympathetic as well as sympathetic divisions located at the junction of neuromuscular belonging to somatic nervous system) receptors (Savarese, 2005). Mechanism of Organophosphate insecticides in toxicity refers to the acetylcholinesterase inhibition, causing an accumulation of neurotransmitter acetylcholine as well as continuous stimulation of receptors of acetylcholine. The Organophosphate insecticides is said to induce the parasympathetic nervous system with an enzyme named phosphorylating acetylcholinesterase (that binds irreversibly along with that of acetylcholinesterase) at every nerve ending. The enzyme Acetylcholinesterase is breaks down acetylcholine within the junction of neuromuscular. It causes a loss of acetylcholinesterase in order that effecter organ gets overstimulated with immense of acetylcholine at nerve ending (Hui, 2012). The mechanism is said to impact both muscarinic as well as nicotinic receptors within parasympathetic as well as sympathetic systems along with that of neuromuscular junctions. Organophosphate insecticides usually resemble that of clinical drugs named anticholinesterase in context to its action. Thus, the clinical drug groups are quite similar in context to their actions- physostigmine, neostigmine; but these drugs often have reversible impacts(Jusko, 2012). It shows that these drugs may possess capability to displace the insecticides from those enzymes, thereby reactivating the activity of cholinesterase. Further, drug like echothiophate iodide also an irreversible organophosphate anticholinesterase used clinically. The standard process of treatment for Mr FT would include reactivation of inhibited acetylcholinesterase along with an antidote named oxime and that of pralidoxime as well as reversing of biochemical impacts of acetylcholine along with atropine. Pralidoxime Iodide: Pralidoxime is said to reverse depression of cholinesterase and so relieves both muscarinic as well as nicotinic impacts of poisoning. It is said to work with reactivating of cholinesterase including that of slowing the process of ageing of phosphorylated cholinesterase towards a non-reactivatable form (Lemley et al., 2010). Atropine Sulphate: The purpose of atropine antidotal therapy in case of organophosphate poisoning includes antagonising the impacts of increased concentrations of acetylcholine in organs with muscarinic receptors. This serves as strong blocking agent for acetylcholine but ineffective to reverse the process of inhibition of cholinesterase. The chronic disease that has been affecting people from all the age group is asthma. There is obstruction in the flow of air. It shows problems in the respiration of the individual. The National Health campaign aims at management of the Asthma of the individuals. This will improve the well being of the individuals and the severances of the symptoms of the disease will be reduced. a.) Management of Asthma long term mission The chronic symptoms causing discomfort such as breathlessness, coughing should be averted. The normal function of the pulmonary has to be preserved. Exercise has to be done to preserve the normal activity (LeWitt, 2014). The need for the visit to the emergency departments at hospitals has to be avoided. Medication with little side effects has to be taken. The management technique of families for asthma has to be followed. b.) Treatment of acute Asthma First line therapy The inflammation of the lungs is stabilized by this technique. This is done by the passage ways of the lungs are prevented from getting inflated. This is achieved by the inhalation of corticosteroids or the prophylactic agents for the attacks of asthma. An inhaled 2 agonist has to be used if the propensity to exposure increases. The bronchodilators can be combined with the nebulizer to for a patient suffering from severe attack of asthma. Oral administration of corticosteroids during the asthmatic attack can be helpful (Ra, 2014). This has helped to stop the saturation by 93%. Rectification of the hypoxic condition of a child is important to prevent the child from asthmatic attack. The treatment to the child can be provided by treating with 2 agonists. The oral way of treatment via the corticosteroids is also useful. The metered dose salbutamol inhaler is very effective in getting positive results. The inflammation of the passage of the airway characterizes Asthma. This concludes in attack by asthma creating an obstruction with the airflow through the air ways. The bulge of the mucous membrane causes the obstruction. The fluid inside the airways which is inflammatory and the muscle contraction also causes obstruction. Children Can have severe obstruction in the flow of air for having a small way for passage of air. If not avoided then smoking, respiratory infection, air pollution, fumes, airborne allergen, certain type of foods and dusts contributes to the attack in BBs in asthma. The inhale corticosteroids are very effectual (anti-inflammatory potential) manager for the control in long-term and are widely chosen by patients who grow to unrelenting asthma syndrome. Nevertheless, the use of inhaled corticosteroids therapy for control in long term concentrated on treatment of inflammatory system and has the ability to prevent the inflammation occurrence and reduce the inflammatory airway, while preventing serious symptoms of asthma and preserving control over them (Seyberth, Rane and Schwab, 2011). a) According to the encountered short-term effects after using corticosteroids inhale, the range of likely negative effects is expected to develop infections which are opportunistic in nature like the Candida albicans pharyngeal and the croaky voice concluding the immune function being suppressed of pharyngeal mucosa after utilizing the corticosteroids (Scully, 2008). It should be kept in mind as in case of the children these agents stifle the hypothalamic-pituitary region particularly when they are directed for a long time period at a very high dose. Children who suffer from mild asthma were observed with growth disturbance in short term which is a side effect of inhaling corticosteroids (Johnson, 2010). According to some data there is a propensity for affecting bone mineralization after using corticosteroids. It can also increase in the suppression of adrenal and syndrome of drug-induced Cushings as a termination (Walsh, Czervinske and DiBlasi, 2010). b) In accordance to Short term consequences which are connected with the 2 agonists, certain effects of short term were scrutinized like Tachyphylaxis that is the reduced responsiveness to the medication because of desensitization and down-regulation of the receptors in the tangential lymphocytes and the receptors present in the lungs. There are also some other negative effects considered to be minor such as, metabolic effects, headache, tremor and palpitations which are encountered relating to the quantity of the doe used (Walsh, n.d.). The ICS are the most chosen regimen for therapeutic conditions in case of children chronic asthma and as the provider of the most accessible anti-inflammatory treatment. The use of long term medication of inhaled corticosteroids ascertains potential negative effects especially on the adrenal function, the velocity of growth and the obstruction of linear growth, ocular disorders and osteoporosis. According to various proofs demonstrated that the agent of potent anti-inflammatory suppress the region of hypothalamic-pituitary which is not a sustained effect for a long term as the child reaches the height of normal as in mentioned in the 4a question. Due to the delivery of medicine being quicker after using inhaler than a nebulizer, it is preferred by many. Moreover it is a small device that can be easily carried during emergency and other necessary requirement moment. A device used with metered-dose inhalation in combination for satisfactory inhalation is known as spacer. It is a satisfactory inhalation for individuals who are not comfortable with coordination of hand-breath. However the BBs acute incident managing health team applied both spacer and inhaler ( for administering the B2 inhaled agonist by MDI) only for the reason that they permitted for better medication deliverance by increased inhalation and actuation coordination, infectious haze as it releases inhalation of meter dozed and allows having drugs with no enduring, remain in the mouth. The team of managing dis not utilizes the nebulizer because obvious benefits were not ascertained in comparison to spacer and inhaler. As moisture and warmth is combined with the use of nebulizer, it is often remarked for carrying danger of microbial contamination. In case of asthma that causes threat to life nebulizer becomes valuable when through oxygen the b2 agonist high doses are necessarily controlled. In case of Pediatric urgency, Nebulization becomes less efficient. It becomes hard to control and another disadvantage is that it is expensive cannot be transferred or carried like spacer or meter-dose inhaler and similar devices. The corticosteroid hydrocortisones strategic control helps in recovering during or after and attack of acute asthma with the duration and sternness of the acute attack and it helps to prevent relapse. The Hydrocortisone attains prompts condition of allergy and swelling in the body. In response to an allergen or irritant this hormone is discharged in the body. With the reason of providing corticosteroid to the asthmatics is to make the lining of airways calm which has been influenced by atmospheric change or irritant. When the patient is under the combined treatment for recovery form an attack of acute asthma, it is crucial to control the corticosteroids level in the body since a sudden treatment halt may conclude in shock, vomiting nausea and can eventually conclude in disturbance in the functions of adrenal. The controlling of dosage would reduce the negative effects like adrenal axis of hypothalamic-pituitary, fractures and osteoporosis because of mineralization of bone in low density and developmental disturbance. The subsequent required to be monitored: The rhythm and rate of the cardiac The blood pressure The levels of oxygen concentration and The sounds of chest It is so because they are crucial signs that will alter in retort to the treatment that allows medical practitioner for continuation and adjustments for necessary treatments. References Bae, S., Yang, K., Aryal, D., Kim, Y. and Lee, M. (2009). Pharmacokinetics of amitriptyline and one of its metabolites, nortriptyline, in rats: Little contribution of considerable hepatic first-pass effect to low bioavailability of amitriptyline due to great intestinal first-pass effect.Journal of Pharmaceutical Sciences, 98(4), pp.1587-1601. Banker, M. and Clark, T. (2008). Plasma / Serum Protein Binding Determinations.Current Drug Metabolism, 9(9), pp.854-859. Caldwell, J. (2005). GW280430A: Pharmacodynamics and Potential Adverse Effects.Anesthesiology, 102(4), pp.862-863. Chengliang, T. (2012). Determination of plasma protein binding rate of vitexin.China Journal of Chinese Materia Medica. Doern, G. (2001). Fluoroquinolone Pharmacodynamics and Efficacy.Chest, 120(1), pp.319-320. EL-LAKKANY, N. and NOSSEIR, M. (2007). Pharmacodynamics of pentoxifylline and/or praziquantel in murine schistosomiasis mansoni.APMIS, 115(3), pp.184-194. Hee Lee, Y. (2000). Regional oral absorption, hepatic first-pass effect, and non-linear disposition of salmon calcitonin in beagle dogs.European Journal of Pharmaceutics and Biopharmaceutics, 50(2), pp.205-211. Hui, K. (2012). Determination of plasma protein binding rate of isopropylidene-shikimic acid.China Journal of Chinese Materia Medica. Jusko, W. (2012). Changes to journal of pharmacokinetics and pharmacodynamics.Journal of Pharmacokinetics and Pharmacodynamics, 39(1), pp.1-1. Lemley, C., Wilmoth, T., Tager, L., Krause, K. and Wilson, M. (2010). Effect of a high cornstarch diet on hepatic cytochrome P450 2C and 3A activity and progesterone half-life in dairy cows.Journal of Dairy Science, 93(3), pp.1012-1021. LeWitt, P. (2014). Levodopa therapy for Parkinson's disease: Pharmacokinetics and pharmacodynamics.Movement Disorders, 30(1), pp.64-72. Ra, I. (2014). Results on the Convergence of Braitenberg Vehicle 3a.Artificial Life, 20(2), pp.223-235. Savarese, J. (2005). GW280430A: Pharmacodynamics and Potential Adverse Effects.Anesthesiology, 102(4), pp.863-865. Tominaga, M. (2002). Effect of portal vein embolization on function of the nonembolized lobes of the liver: Evaluation by first-pass hepatic lidocaine extraction in dogs.Surgery, 132(3), pp.424-430. Wright, D. (2000). Application of fluoroquinolone pharmacodynamics.Journal of Antimicrobial Chemotherapy, 46(5), pp.669-683. Yang, Z. and Rodrigues, A. (2010). Does the Long Plasma Half-Life of 4-Hydroxycholesterol Impact Its Utility as a Cytochrome P450 3A (CYP3A) Metric?.The Journal of Clinical Pharmacology, 50(11), pp.1330-1338. YOKOMASU, A., YANO, I., SATO, E., MASUDA, S., KATSURA, T. and INUI, K. (2008). Effect of Intestinal and Hepatic First-pass Extraction on the Pharmacokinetics of Everolimus in Rats.Drug Metabolism and Pharmacokinetics, 23(6), pp.469-475. Scully, C. (2008).Oral and Maxillofacial Medicine: The Basis of Diagnosis and Treatment. 2nd ed. Churchill Livingstone, p.408. Seyberth, H., Rane, A. and Schwab, M. (2011).Pediatric Clinical Pharmacology. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. Walsh, B., Czervinske, M. and DiBlasi, R. (2010).Perinatal and pediatric respiratory care. St. Louis, Mo.: Saunders/Elsevier. Walsh, B. (n.d.).Neonatal and pediatric respiratory care.

Wednesday, December 4, 2019

Two ways to belong to america bharati free essay sample

In the story â€Å"two ways to belong to America† the author and narrator Bharati addressed an issue of images of immigrants in America, and what it truly means to belong to a country. In Bharati short story â€Å"two ways to belong to America† she talks and her and her sister experience as first time immigrants migrating from India to America. At their arrival to America they were similar in a lot of ways, appearance and attitudes-views and sentiments. They were both seeking degrees-Mira in child psychology and pre-school education, bharati went on to peruse a degree in creative writing. After they obtained their degree’s they were to return to India and marry, a man of their fathers choosing. The second part of this plan the two sisters aborted – Mira, after successfully gaining her degree in child psychology and preschool education and Preferring to be set in her ways married a young Indian man pursuing his business administration degree at Wayne’s university. We will write a custom essay sample on Two ways to belong to america bharati or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Bharati while obtaining her degree in creative writing married a fellow American student of Canadian heritage. Both of them then would be successfully married for thirty plus years and still maintain contact with each other; however, the narrator Bharati sees that as the only similarity that they have as immigrants coming from India to America. Bharati being the more outgoing and open-minded sister of the two, choose to welcome as much change as a new continent could offer, obtaining her green card then later her citizenship. She welcomed the difficulties of marrying a man from a different culture, wanting all the challenges that were accustomed to adapting to the American culture. She moved around in to different states, and even went to live in husband family’s homeland-Canada. She wanted to set roots in the country she lived in, vote and make a difference in any way that she could. She simply wanted to feel like she belonged. Mira on the other hand, being more of an introvert and a patriot of her county/culture felt it necessary to never involved in American culture and felt contentment with her labor certification. She stuck to her roots and her ancestral culture, but contributed significant amount of her  expertise in child psychology and preschool education to American educational system and nationally has been recognized for her efforts. The Two sisters could not be any more different in their experiences of America. In this time, new laws were being established about the issues of possessing a American citizenship/green card verses just simply obtaining a right to word certification. This cause Mira to become irritated at the way she felt America was treating its hardworking immigrants, however Bharati always being able to look at both sides of an issue objectively, did not see it that way. she tried to urge her sister to get a green card so that she would still be eligible for benefits that came with being an American citizen/green card holder , she replied she would, just until she was ready to go back to her country she’d change her citizenship back to being a citizen of India. Bharati then saw her sister in a different light, they certainly was not the same. Where she was passionate about being in a new country her sister preferred to be like an exile, living in a country but not of the country. In conclusion, I agree with both Mira and Bharati I believe that when one has willingly come to a country, one must adapt, however one must always maintain an identity that signifies their background and ancestry†¦never fully giving in to both but finding a balance that suits you.